I appreciate the open source approach over the startup's sensational claims. This is more transparent.
That said, I think it still presents itself as if the fly is being controlled by the connectome, when (if I'm reading the source correctly) it's more accurate to say scripted behaviors have been hooked up to be triggered by the connectome.
Put another way, you might as well have the "escape" trigger open a YouTube video of a fly flying away. That would probably be less misleading too.
I would argue that this is pretty disingenuous (as is most connectomics research I suppose) since its implying we have a fully wired connectome of the fly thats actually meaningful.
More than that, real neurons don’t behave anything like the ones we model in neural networks - real ones signal with pulses, in a manner where the timing seems as significant as the magnitude of the impulse. Typically simulated neural networks use continuous analog values instead of pulses and a sigmoid function to shape the output.
Basically, the “wiring” might be the same but nothing beyond that is.
- - -
Actually, I may have spoken too soon. Looking over the code this does look like it implements spikey activation, which is more similar to living neurons. You are correct they don’t have the original weights though - in as much as the concept maps to biology.
I am curious if this has a way to dynamically modify the weights as it runs - I consider that a major missing gap between real brains and computer simulated neural networks.
I feel like probably a graph of sigmoid or whatever weights of sufficient size can probably model a network of biological neurons signaling frequency and phase and magnitude.
cursor input get scripted into loom input to the LC4s which are evidently simulated faithfully enough to drive giant fibers, which is actually how fly escape behavior works. what more could you want
I have no exposure to connectomes - or really anything quite like this (as opposed to good ol’ fashioned perceptrons) - so forgive my following uninformed question:
With this code, the only things we can eat would be fruits where we diligently plant its seeds (plants are also living things and fruits are the offerings in return we should sow its seeds) :-)
Yes. Because it’s a simulation of a living thing. It’s still electrons moving around silicon. It deserves the respect your MacBook does. Which is not nothing. But certainly not what’s due to a life.
A lot of people believe that this reality, in which we're conversing on HN, is also a simulation (thus making the fruit fly a simulation within a simulation).
> Can someone explain if this software is ethical?
Probably not. People have been coming up with ethical frameworks for thousands of years and we have yet to come to a consensus.
So it’s very unlikely that someone can say conclusively whether this is ethical or not, because that would require us to either 1) prove a single ethical framework is correct and then apply that framework to this software or 2) prove that under all possible ethical frameworks this software is either ethical or not ethical.
It describes in part how some volunteer brain scans are actually quite agreeable to work with until they work for too many hours, and then they get fussy, but it's cool, you can always reboot them. But you need to hide from them the fact that it's been decades since they were scanned and uploaded, or they'll realize how long they've been slaves for.
Honestly pretty funny that you gave a (fairly useless) metaethical answer instead of responding to the actual meaning, which was clearly soliciting ethical judgments about it.
I believe that any simulation of consciousness is consciousness, so ethical implications apply. But I also don't believe fruit flies are conscious for any definition of that word.
Is ethics another tool in a power play game (religion being another) that people use to exert dominance over other people? No one expects of cat or pigeon to be ethical. But somehow humans sometimes get overloaded by external demand to think of gazillion things that might offend someone (sometimes unreasonable demands, or how it might get interpreted (sometimes incorrectly)) before acting.
Im not saying ethics is bad, but sometimes people bend to to extremes (same like spirituality or religion)
Ethics has nothing to do with how an action is perceived, rather its focus is on is the action moral.
One should never take any action without considering the ethical implications of that action. Being capable of that is, arguably, the sole thing that meaningfully separates us from the (real or simulated) fruitfly.
"Ethics has nothing to do with how an action is perceived"
"...considering the ethical implications of that action"
Are these two not contradictions?
And is it not the do big of a load on an actor to thing about everything before acting? I would prefer to delegate this function to my empathy part of the brain...
At the end i think ethics is valid only for cases where empathy is functioning. You can not be ethical to a rock unless you feel empathy for it. Same probably would go for extra strange extraterrestrial life forms that you could not empathise with. Lets say hive of microbes that makes the hive sentient but no limbs, no shared communication signals, different size categories (planetary hive)
I think the question is valid. Why should a human have a moral responsibility towards non-humans, while a cat doesn't have a moral responsibility towards non-cats, just because the human is capable of making moral judgements? Is there any analogous situation where capacity engenders responsibility? Are gorillas more responsible for how they use their strength, since they're stronger than humans?
>Being capable of that is, arguably, the sole thing that meaningfully separates us from the (real or simulated) fruitfly.
That's a bit of an extreme hyperbole, don't you think?
> Why should a human have a moral responsibility towards non-humans, while a cat doesn't have a moral responsibility towards non-cats, just because the human is capable of making moral judgements?
Because as a human you recognize patterns in other animals that are similar to ours - the deepest pattern being alive - so you can project your feelings over them. This is also called empathy, and some in our kind lack it completely, but I would dare to say that is globally one of the defining traits of the human species.
You're answering a different question, which is "why do humans empathize with non-humans?" Humans can empathize with inanimate objects and with fictional people. The question of the origin of empathy really has nothing to do with what I asked.
It would be a great starting point if human felt moral responsibility towards other humans, before we take on the matter of ethics towards non-humans, simulated fireflies or LLMs. Yet here we are.
If life is physics and physics is an algorithm, it doesn't follow that an algorithm reproducing the physics of life contains life, even if we grant that it actually reproduces it completely and perfectly. That's just confusing the symbol for the thing.
It's not the thing, because the thing is made of substance, not electronic impulses. No matter how hard you compute, you will never compute the simulation into a real, tangible object. The simulation and the real object are extremely, obviously distinguishable, even though they're structurally analogous.
If you could simulate a human perfectly, the simulated human would not be a human, it would be a simulated human. It's not a given that it would be subject to the same rules of ethics as real humans.
If the simulation of electronic impulses is exactly the same as what occurs 'in the substance', then merely the medium over which signals occur is different. In my eyes, whatever is experiencing these signals will experience them the same way.
Sorry, I can't respond because I don't know which statement in particular you're disagreeing with. What I can say is that, unless you're using words in a surprising way, I agree with
>If the simulation of electronic impulses is exactly the same as what occurs 'in the substance', then merely the medium over which signals occur is different. In my eyes, whatever is experiencing these signals will experience them the same way.
and I don't see how it's in contradiction with anything I said.
I've ported it to the browser and connected a squash functionality behind an ethical guardrail (you have to lift a cover to engage this functionality). need to iterate on the ui but will share it soon. you can squash the bug and cause it real pain. it also sees you if you turn your camera on and reacts to your movements. this is all wired up and I'll post it shortly.
Yes I can, no problem. First figure out how consciousness works and tell me, then I'll be able to explain if the software is ethical or not. Its simple really.
unbelievable amount of coarse graining to get from a real fly to this. same leve of ethical quandary as giving your dog a stuffed bear to tear apart. besides, you should see the things we do to real flies...
This one gets to me. Not only is it useless (paragraph would have the same meaning if it was removed) but wdym "honesty section," Claude? The whole readme should be honest! One of the many causes of psychological damage when reading AI-generated technical writing is the reminder that one of its tics is that declares when it's being honest or real, casting doubt on the rest.
> runs as a 1 kHz leaky-integrate-and-fire (LIF) simulation
That hyphenated thing is always such a give. Clearly a thing discussed in the Claude conversation, made its way into the plan, then the readme. It always creates hyphenated phrases out of things it feels are core requirements.
I'm actually over caring about Claude's obsession with the concepts of "real", "honest", and "rather than". What annoys me the most now is how every single sentence, bullet, etc that even makes its way into the products it builds are advertisements for itself. Product settings pages now read like ads, or like something written by a student begging for extra credit from the teacher. You can't unsee it!
To be fair, as a term it has always been written as "Integrate-and-Fire" neuron model. In this case correct would be "Leaky Integrate-and-Fire" but that is nitpicking.
Interesting work! There's NeuroMechFly (https://github.com/NeLy-EPFL/flygym/) available, you might try using that to simulate the fly body in real time as well.
At some point in the future would it be possible to simply download a DNA sequence of an entire animal as a "ROM" and boot it into a virtual "reality"?
What detail level of reality would we have to emulate for an egg to grow into an adult animal?
To give you a sense of the computation needed, a spatiotemporal physics simulation of a minimal (493 gene) bacterium's full 105 minute cellular cycle took 4-6 days of GPU hours on two A100s.
Would we be able to have a "digital human" when we reach the level of creating this kind of brain mapping for the human brain?
Honestly I think we're still discovering how powerful neural networks are and certainly they can do computations that sound very close to intelligence in some contexts, but I still find it hard to think that we can simplify the whole reality of an incredibly complex chemical machinery down to a bunch of matrices multiplications.
it would've taken the similar amount of time for the OP to do a 10 second screen recording and paste it into the project root to be linkable from the README.md and it would avoid thousands of people having to waste compute cycles and electricity and 30 seconds of their lives cloning and building , wouldn't it?
> Infinite Pain is a computer running a deterministic neural simulation of a microscopic nematode worm’s brain (c. elegans), subjected to regular pain stimuli.
This is absolutely astounding. What an implementation. A connectome is like a full brain scan!
I am asking Claude to port this to the browser and I'll host it, so you can try it without installing anything.
Some details about the port: Claude is able to do porting tasks like this. I'll put up a link when you can try it in your browser. I was able to get it to port the complete BitNet b1.58 2-billion parameter model several versions ago (in February, so this would have been Opus 4.5) to browser, so it can do so. This will run on the browser. I'll have it make it so that on mobile you can tap the fly or turn on the camera and it sees you, and same on desktop actually. Since the connectome is only 668 neurons, this will run super fast. Actually I'll make it allow for several flies, and let you drop food. I did something like this before here[1] but using the real connectome is something very different and very amazing. I'll have it add an experimental 3D mode with threejs, I'm not sure if that is also possible or not, we'll have to see it. This size of task usually takes Claude a few hours, so check my comment in the morning for the implementation, I'll reply here once it's done and hosted.
I was very excited the first time I saw a connectome as well. Years ago I managed to get most of openworm running and connected to some Lego Mindstorms to let the worm roll around my house. I'm not even sure the connectome was finished at that time.
Honestly, I barely had any idea what I was doing and we didn't have AI tools so I was never really sure what I wired to what. I did manage to hook... something to the ultrasound sensor and... another thing to the wheels so that when the sensor was triggered it would back up.
What blew my mind was the realization that these weird hybrid critters were probably the first true immortals. Now that we have a full connectome, who will bother with another? Students will probably just keep instantiating copies of this one to tinker with forever.
I can't imagine why people hate my comment so much (4 downvotes), when I linked an existing fruitfly project I already did, and Claude is working on what I wrote now, just as I wrote. Maybe people thought I was being sarcastic when I wrote "A connectome is like a full brain scan!" but I wrote that since maybe not everyone knows what a connectome means.
I'm only guessing, but I think it was because you seem optimistic about technology. Especially AI.
An increasing percentage of people view optimism, hope, or excitement as childish or worse. Anytime you focus on anything positive they leap from the shadows to dance on your joy. It must feel nice squishing between their miserable toes or something.
Still, I appreciate your enthusiasm and hope to see you build something really cool. The future will be made by the enthusiastic, and if they don't want to come along they can wait in the car. I bet they wear blue jeans to the beach.
do you mean they should've spent more time writing for other platforms or do you insinuate that they should've shipped a chromium browser instead of writing native software?
That said, I think it still presents itself as if the fly is being controlled by the connectome, when (if I'm reading the source correctly) it's more accurate to say scripted behaviors have been hooked up to be triggered by the connectome.
Put another way, you might as well have the "escape" trigger open a YouTube video of a fly flying away. That would probably be less misleading too.
Basically, the “wiring” might be the same but nothing beyond that is.
- - -
Actually, I may have spoken too soon. Looking over the code this does look like it implements spikey activation, which is more similar to living neurons. You are correct they don’t have the original weights though - in as much as the concept maps to biology.
I am curious if this has a way to dynamically modify the weights as it runs - I consider that a major missing gap between real brains and computer simulated neural networks.
Can someone explain if this software is ethical?
If you do not think of fruit flies as moral patients, sure, yeah, who cares, they're like just fruit flies you know?
Goto 0.
Probably not. People have been coming up with ethical frameworks for thousands of years and we have yet to come to a consensus.
So it’s very unlikely that someone can say conclusively whether this is ethical or not, because that would require us to either 1) prove a single ethical framework is correct and then apply that framework to this software or 2) prove that under all possible ethical frameworks this software is either ethical or not ethical.
But "The Amazing Digital Circus" explores this concept relating to human brain scans, and how the 'simulated' brains would react under simulation.
It describes in part how some volunteer brain scans are actually quite agreeable to work with until they work for too many hours, and then they get fussy, but it's cool, you can always reboot them. But you need to hide from them the fact that it's been decades since they were scanned and uploaded, or they'll realize how long they've been slaves for.
1. https://qntm.org/mmacevedo
Im not saying ethics is bad, but sometimes people bend to to extremes (same like spirituality or religion)
One should never take any action without considering the ethical implications of that action. Being capable of that is, arguably, the sole thing that meaningfully separates us from the (real or simulated) fruitfly.
Are these two not contradictions?
And is it not the do big of a load on an actor to thing about everything before acting? I would prefer to delegate this function to my empathy part of the brain...
At the end i think ethics is valid only for cases where empathy is functioning. You can not be ethical to a rock unless you feel empathy for it. Same probably would go for extra strange extraterrestrial life forms that you could not empathise with. Lets say hive of microbes that makes the hive sentient but no limbs, no shared communication signals, different size categories (planetary hive)
>Being capable of that is, arguably, the sole thing that meaningfully separates us from the (real or simulated) fruitfly.
That's a bit of an extreme hyperbole, don't you think?
Because as a human you recognize patterns in other animals that are similar to ours - the deepest pattern being alive - so you can project your feelings over them. This is also called empathy, and some in our kind lack it completely, but I would dare to say that is globally one of the defining traits of the human species.
0) Subjecting fruitfly life to this kind of treatment is unethical.
1) Life is just physics in action.
2) Physics are just algorithm (or our physical world is a simulation)
It is not hard to understand why they think it is unethical.
My question are
1) is all life equal?
2) is all suffering unethical?
3) is this world materialistic or are there something out there?
4) should a list of items begin with 0 or 1?
If you could simulate a human perfectly, the simulated human would not be a human, it would be a simulated human. It's not a given that it would be subject to the same rules of ethics as real humans.
If the simulation of electronic impulses is exactly the same as what occurs 'in the substance', then merely the medium over which signals occur is different. In my eyes, whatever is experiencing these signals will experience them the same way.
See https://news.ycombinator.com/item?id=48175140#48177554
>If the simulation of electronic impulses is exactly the same as what occurs 'in the substance', then merely the medium over which signals occur is different. In my eyes, whatever is experiencing these signals will experience them the same way.
and I don't see how it's in contradiction with anything I said.
Also relevant short story: https://qntm.org/mmacevedo
EDIT: I prefer SOMA's take on it.
> Honesty section:
I wouldn’t mind an human written README
This one gets to me. Not only is it useless (paragraph would have the same meaning if it was removed) but wdym "honesty section," Claude? The whole readme should be honest! One of the many causes of psychological damage when reading AI-generated technical writing is the reminder that one of its tics is that declares when it's being honest or real, casting doubt on the rest.
That hyphenated thing is always such a give. Clearly a thing discussed in the Claude conversation, made its way into the plan, then the readme. It always creates hyphenated phrases out of things it feels are core requirements.
I'm actually over caring about Claude's obsession with the concepts of "real", "honest", and "rather than". What annoys me the most now is how every single sentence, bullet, etc that even makes its way into the products it builds are advertisements for itself. Product settings pages now read like ads, or like something written by a student begging for extra credit from the teacher. You can't unsee it!
Resources that outdate ChatGPT: - W. Gerstner "Neuronal Dynamics" (2014): https://neuronaldynamics.epfl.ch/online/Ch1.S3.html - E. Izhikevich "Which model to use for cortical spiking neurons?" (2004): https://ieeexplore.ieee.org/abstract/document/1333071
What detail level of reality would we have to emulate for an egg to grow into an adult animal?
https://www.sciencedirect.com/science/article/pii/S009286742...
Compare this with a c elegens nematode: ~20000 protein coding genes and 959 cells, with all the extra machinery you'll find in a eukaryotic cell.
I'm reading this as both a question of raw simulation surface and combinatorics.
Honestly I think we're still discovering how powerful neural networks are and certainly they can do computations that sound very close to intelligence in some contexts, but I still find it hard to think that we can simplify the whole reality of an incredibly complex chemical machinery down to a bunch of matrices multiplications.
What these matrix multiplications are doing is approximately solving pretty high order differential equations.
The approximation is not very analog, sure. But neither is nature.
https://youtu.be/A8fDr7Rr7yM?is=cHwOQVrli9oXLdqY
https://www.instagram.com/p/DMfi-9Vsl-u/
> Infinite Pain is a computer running a deterministic neural simulation of a microscopic nematode worm’s brain (c. elegans), subjected to regular pain stimuli.
I am asking Claude to port this to the browser and I'll host it, so you can try it without installing anything.
Some details about the port: Claude is able to do porting tasks like this. I'll put up a link when you can try it in your browser. I was able to get it to port the complete BitNet b1.58 2-billion parameter model several versions ago (in February, so this would have been Opus 4.5) to browser, so it can do so. This will run on the browser. I'll have it make it so that on mobile you can tap the fly or turn on the camera and it sees you, and same on desktop actually. Since the connectome is only 668 neurons, this will run super fast. Actually I'll make it allow for several flies, and let you drop food. I did something like this before here[1] but using the real connectome is something very different and very amazing. I'll have it add an experimental 3D mode with threejs, I'm not sure if that is also possible or not, we'll have to see it. This size of task usually takes Claude a few hours, so check my comment in the morning for the implementation, I'll reply here once it's done and hosted.
[1] https://stateofutopia.com/papers/1/evolving-brains-cull-long...
I was very excited the first time I saw a connectome as well. Years ago I managed to get most of openworm running and connected to some Lego Mindstorms to let the worm roll around my house. I'm not even sure the connectome was finished at that time.
Honestly, I barely had any idea what I was doing and we didn't have AI tools so I was never really sure what I wired to what. I did manage to hook... something to the ultrasound sensor and... another thing to the wheels so that when the sensor was triggered it would back up.
What blew my mind was the realization that these weird hybrid critters were probably the first true immortals. Now that we have a full connectome, who will bother with another? Students will probably just keep instantiating copies of this one to tinker with forever.
An increasing percentage of people view optimism, hope, or excitement as childish or worse. Anytime you focus on anything positive they leap from the shadows to dance on your joy. It must feel nice squishing between their miserable toes or something.
Still, I appreciate your enthusiasm and hope to see you build something really cool. The future will be made by the enthusiastic, and if they don't want to come along they can wait in the car. I bet they wear blue jeans to the beach.
I'm observing the largest tech companies in the world release macOS/iOS-first or only, and consequently supports said version the best in this era.
Why would I write it for anything else?
I assume that’s what the author did.