MRI scans show exercise can make the brain look younger

(sciencedaily.com)

82 points | by amichail 6 hours ago

10 comments

  • zmmmmm 3 hours ago
    > brains that looked nearly a year younger

    Seems like a pretty small effect - if I'm 58 and I have the brain of a 57 year old, and to achieve that I did an entire year of exercise (as was done in this study) ... you'd have to evaluate it against many other things to decide if that was really the easiest way to achieve that result.

    I'm always suspicious of small effect sizes even when they are statistically significant. It just seems like so many confounders could bring about the effect. Here I'd wonder if just the mental challenge of achieving that sustained exercise over a whole year was responsible, since generally speaking, any mental challenge you undertake on a regular bases improves overall cognition.

    They try to argue their way around this:

    > "Even though the difference is less than a year, prior studies suggest that each additional 'year' of brain age is associated with meaningful differences in later-life health,"

    But it just begs the question, if you think that then go measure those things with your study.

    Of course I'm not in any way arguing against exercise. Adding at least a baseline level of exercise into your lifestyle is the most impactful health intervention anybody can do after age 40 I believe.

    • N_Lens 30 minutes ago
      Many such effects compound with time, and every additional year of regular exercise adds compounding benefits in multiple systems across the physiology.
    • derektank 1 hour ago
      >But it just begs the question, if you think that then go measure those things with your study.

      Because randomized control, multi-year, longitudinal studies into behavioral interventions in human beings are incredibly annoying and expensive to run if you want to account for the risk of drop outs and/or non-compliance. They hosted twice weekly aerobic exercise classes for the experimental group (dozens of people) for a year! That’s not cheap by any means

  • dwd 2 hours ago
    The 150 minute moderate to vigorous exercise a week comes up a lot, and for a lot of different benefits.

    There's also heart muscle elasticity:

    https://www.ahajournals.org/doi/10.1161/circulationaha.117.0...

    and reduced dementia risk:

    https://publichealth.jhu.edu/2025/small-amounts-of-moderate-...

  • tgv 59 minutes ago
    This is from the abstract: Engaging in 12 months of moderate-to-vigorous exercise reduced brain-PAD in early-to-midlife adults. The pathways by which these effects occur remain unknown.

    They do not make the claim from the title. Given that the effect is small, it might just be that brain-PAD is sensitive to other factors than age, e.g. exercise. As a matter of fact, this study is decent aupport for that hypothesis.

  • with 1 hour ago
    Neat study, but I always chuckle at these, because has there ever been verified science that shows exercise is unhealthy? (besides overtraining)

    The general consensus should just be exercising is good for you, that's it, done.

    • cj 37 minutes ago
      You could look at the inverse: Not exercising causes the brain to look older. Knowing all of the ways not exercising is harmful is probably a good thing.

      But I agree, it would be better if everyone exercised!

  • vonnik 2 hours ago
  • strontium_90 3 hours ago
  • slwvx 4 hours ago
    Can exercise make the face look younger? Or the body? Is exercise the best makeup? ;-)
    • piker 3 hours ago
      Running makes you look older, unfortunately.
      • lostlogin 3 hours ago
        Cycling too.

        The standard being 20kgs under weight, skin baked like old leather, and a previously broken collar bone.

        But, nothing beats it.

      • eaurouge 2 hours ago
        So this is why 30/40 yo track athletes look older than their age mates? Right.
    • MattGaiser 3 hours ago
      There seems to be abundant evidence that exercise is often the best solution for any number of things.

      The problem is that doing it sucks.

      • shoobiedoo 41 minutes ago
        Kettlebells are the perfect middle ground for me. Dynamic movements, easy to incorporate strength gains, very little floor space required and one kettlebell is enough to get started. After a few years of kettlebells I feel like my lower back is made of titanium.

        Downside is there is a fairly steep learning curve to use them without injury.

      • oatmeal1 3 hours ago
        Exercise doesn't suck, land use policies generally just don't prioritize good places for the fun kinds of exercise.
      • conception 3 hours ago
        Doing boring rote movements sucks. There are lots of fun ways to exercise.
      • BLKNSLVR 2 hours ago
        > The problem is that doing it sucks

        I really dislike running for running's sake. But I love inline skating. Did a 20km route yesterday, did 43km a fortnight ago (which was admittedly too far for where my stamina is at). One of the things about skating (and this would also be true for cycling) is the different perspective it provides if you normally get around your local area in a car. You get to see the same places from radically different angles, depending on what paths are suitable to the mode of transport. Just going slower on or next to the road you get to see more detail, but footpaths and other tracks are often (possibly not the right terminology, but) 'off the beaten track'. In inner suburban Melbourne (whilst holidaying there) I chanced upon a relatively unpopulated footpath alongside a river / drain that took me 15km into the city, and it was (in parts) both peaceful and beautiful, despite really not being that far away from main roads / highways / freeways.

        A lot of people like cycling, can be done individually or in any sized group.

        Tennis is mostly individual (although an opponent is required), but I play in a team and enjoy the combination of singles, doubles, and an overall team result.

        Football, soccer, rugby can be physically brutal, but are team sports that have a (forced) social aspect if that's an unmet need. Volleyball is a bit less intense. Table tennis. Lots of options for different sports that cater to different levels of physical stress.

        Find a local park that has a basketball ring and just shoot hoops with yourself regularly. It at least gets you out of a chair and moving both arms and legs.

        If you don't (think you) like any of those things, then you gotta do the hard yards to find that one rare thing you do like. It could just be something that you can find an appropriate level of progression that gives you 'that feeling'. I think that's what got me into skating late in life - I was terrible at it as a kid, but kinda forced into giving it another go as an adult, and within a couple of hours I was already better at it than in my childhood. It was a sense of accomplishment achieved in a relatively short term (= addicted? maybe).

        Find your healthy addiction.

      • lostlogin 3 hours ago
        Find a better way of exercising.

        There is something out there that suits, surely. Sometimes it’s just a step removed.

        • cj 30 minutes ago
          And importantly: stick with it for a few weeks before deciding whether you enjoy it. Virtually no one falls in love with the gym (or whatever fitness activity) the first time they walked in. Getting started isn't always fun. But over time it can become very rewarding.
      • SecretDreams 2 hours ago
        Play soccer twice a week. It's high intensity cardio, normally 60-90 mins tops. Sometimes beers after. And actually fun. Even in a coed league or an adult (min age) league. It's a great time. Bonus points - you'll possibly look more athletic if you keep at it long enough and don't over indulge in those beers!
  • RickJWagner 4 hours ago
    That’s awesome!

    The benefits of exercise against aging, mental illness, etc are numerous and well documented. Everybody should do it.

    • Mars008 1 hour ago
      If that was true athletes would be the youngest, mentally healthiest, and in many other ways better than average. But that's not the case if you look at them. My guess exercise is beneficial only to some level, after that it has a big toll on everything. Including IQ, mental and general health, and so on.
      • derektank 48 minutes ago
        >My guess exercise is beneficial only to some level, after that it has a big toll on everything. Including IQ, mental and general health, and so on.

        What reason do you have for thinking this? As far as I’ve read, there’s no indication that athletes perform worse than the population average on any of these metrics.

        Athletes outperformed non-athletes on standardized tests in a 2014 study of Texas high schoolers.[1] Professional soccer players/footballers outperform the population average on a variety of cognitive assessments.[2] Sub-4 minute mile runners have better longevity and lower risk of cardiovascular disease than average.[3] With the exception of contact sports like American Football which involve serious risks of injury, I can’t think of any example of elite athletes that are worse off on quality of life metrics than average people.

        [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC4831893/

        [2] https://www.pnas.org/doi/abs/10.1073/pnas.2415126122

        [3] https://pubmed.ncbi.nlm.nih.gov/38729629/

      • esperent 33 minutes ago
        It is the case, actually.

        https://www.sciencedirect.com/science/article/abs/pii/S00256...

        Here's another study, although for some reason it's 95% male, it shows athletic men live an average 3.5 years longer. It also shows athletic women live 0.7 years less, but due to the low number of females in the study I wouldn't read much into that.

        https://pmc.ncbi.nlm.nih.gov/articles/PMC11979035/

      • galleywest200 1 hour ago
        Being an athlete and doing maintenance exercises are two different levels of exertion.
      • fdsf2 42 minutes ago
        Mike Ohearn.
  • NedF 4 hours ago
    [dead]
  • jvfjllkttg 3 hours ago
    Less wise perhaps.