I wouldn't read too much into the title, the closing parts of the article give a much more balanced take on the whole issue. This study disagrees with some previous work and it's unclear which result makes sense and why. As usual, more research is needed, and while a catchy title is nice, this isn't anything to change your dietary habits by,
On one hand, if I squint hard enough, I can almost see it, but not exactly for the reasons they propose. Potatoes are infamous for having an extremely high satiety index, that is, you feel very full after eating them. If that holds, it would be easy to see how it could lead to weight loss, since you would feel full earlier and thus eat less.
All that aside, almost all of the results they show are deep within statistical error bounds. My weight easily varies 5lbs (2kg) within a week, saying you lost that amount after a month of diet doesn't really say much to me. I could weigh myself a week from now and say I lost that, then one week on and say I regained it.
What isn't mentioned is that bananas and other potassium-rich foods are alkaline, and so can neutralize stomach acid reflux. Acid reflux is a common source of poor sleep quality. So that could be one explanation for the fewer sleep disturbances.
Reflux is solved by MORE acidity or promotion of stomach acid. Lower stomach acid PH means the LES doesn’t close properly. Seems counter intuitive but took me 8 years of symptoms to discover.
Not every case of reflux is caused by the same things. Some people's esophageal sphincter (such as mine does) just... decides to let go at random times. For me, that I can tell, the frequency of that happening isn't really affected +/- by the PH of my stomach acid, but the PH sure has an effect on the consequences.
I am assuming the best thing I can do for it is lose weight, but that's easier said than done.
If you've tried the traditional diet and exercise and couldn't stick to it, don't let the stigma around glp-1s keep you from taking to your doctor about them. They are a powerful tool. Really helped me
I think this is true for a long term solution, but the standard treatment to alleviate symptoms of reflux is to consume antacids, so I think parent's point is still valid.
So hard to teach this to people, even those who've moved past basic understanding. I keep acid/digestive pills near the bedroom in case I have problems with a late meal
They have long term health consequences and reduce your stomach acid quantity enough that the acid doesn't make it's way back up the throat. So it's masking the root cause. The knock-on effect of taking PPIs or H2-blockers is that you end up with lower acidity which means worse food digestion which means being more prone to bugs and bacteria in food not being wiped out before it gets to the small intestine where it can cause bigger issues like SIBO.
Having the right amount of stomach acid and low PH is crucial to keep the whole digestive system, gut motility and more running properly.
Huh. I am admittedly neither a doctor nor chemist, but I was told this by a doctor, and anecdotally bananas seem to help me with reflux. Looking on the web, there does seem to be conflicting advice.
I'd heard claims like that before and I was curious so I googled a bit more.
It sounds like there's this thing "PRAL" or "potential renal acid load" https://en.wikipedia.org/wiki/Potential_renal_acid_load where the affect on stomach acid can be different from a food's pH. But again, the wikipedia article links to some random people's blogs and a single research article from 2019. I'm not sure if this is well supported by research.
Exactly- this is based on how it alters urine pH, and there is a whole alternative medicine thing around assuming this is extremely important- but the entire idea seems unconvincing to me. Both stomach and blood pH are carefully regulated by feedback control and don’t themselves change much based on foods.
It is extreemly important because it is easy to measure and varies wildly based on concious decisions: things that make it easier to sell the snake oil. Blood pressure is another. Many a "tonic" of flavored alcohol seemingly cured symptoms of high blood pressure... long enough to make the sale.
I can see why the directly observable effect could help here, but what are these “alkaline diet” people selling exactly? I’ve mostly seen it just from individuals giving me unsolicited health advice. Also are these people really measuring the pH of their urine?
Whenever I see discussions of GERD I like to bring up this paper (and the reedit discussion around it) where they basically tried a supplement with every likely helper and it worked 100% of the time: https://www.reddit.com/r/GERD/comments/adt6vh/regression_of_...
| The aim of this study was to investigate if a dietary supplementation containing: melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine would help patients with GERD,
| All patients of the group A (100%) reported a complete regression of symptoms after 40 days of treatment. On the other hand, 115 subjects (65.7%) of the omeprazole reported regression of symptoms in the same period
Acid reflux is due to too low stomach acid (too high pH). The lower esophageal sphincter closing as a response to acid (pH) is documented in the literature.
I know this isn't related to potassium directly, but anecdotally I have had success using magnesium supplements for insomnia/improving general sleep quality. I have also been consuming electrolyte mixes containing potassium to help with muscle recovery from training, and have found them to help with physical soreness & general well-being.
I also believe I have an underlying kidney disorder that was causing all sorts of subtle problems and after researching for years decided to try potassium supplements and it relieved the acute symptoms I was having (daytime sleepiness after meals) and also a whole slew of symptoms I didn’t realize I was having (poor workout performance and recovery, constant thirst from sodium/potassium imbalance, heart palpitations, especially at night when lying in bed, temperature regulation when trying to sleep, restless legs at night, and sleep quality).
Sleep was the most surprising. I used to wake at around 3am and just couldn’t get back to sleep. I still wake up to pee, but I get right back to sleep.
The single most surprising thing is the quality of my sleep. I now sleep like a rock. So unbelievably hard. And when I wake I feel so rested and more clear headed. I don’t need to sleep as many hours anymore and feel better than when i would sleep 9 hours.
Recently several sleep studies started talking about how sleep is not a passive activity, but a ‘washing’ of CSF over your brain. I could get some details wrong since I am going off of memory, but I believe the amount of CSF movement and production basically triples when you sleep. I hypothesize that this is simply your bodies way of cleaning the waste products out of your brain. Do you know what precursors are to create CSF? Electrolytes like sodium, potassium, chloride, and bicarbonate. It is my hypothesis that I was ‘using up’ all the potassium available with the first couple of sleep cycles and once it was gone I was unable to effectively create more CSF, rendering my sleep ineffective.
All I need to take is a couple of 99mg tablets right before bed (along with some magnesium chloride) and I sleep like I did when I was 10. I am 57. To say it has transformed my life would be an understatement.
I have every single one of your symptoms and arrived at almost the same conclusion: taking electrolytes tablets intended for workout recovery (just sodium, magnesium and potassium, no sugar) improves alleviates almost all of my symptoms and gives me energy I haven't had since I was 12. I haven't been able to get a doctor to take me seriously for ten years. I will try the potassium + magnesium tablets at night instead of a generic multivitamin. Thank you so much for your comment.
Do you have any additional information about this relationship between CSF and electrolyte deficiency? Do you know anything about possible upstream causes of electrolyte deficiency? Any pointers would be super helpful.
I also started with general “electrolytes” but found that one of my problems was that I was getting way too much sodium and not enough potassium. This was the primary driver of my post-meal somnolence. Most general electrolyte supplements are primarily sodium, and this was exacerbating my symptoms in some cases. I now only eat meals that have a reasonable amount of sodium and then take a couple of potassium tablets a couple of hours after eating if I feel myself starting to get a little sleepy. 30 minutes later I am ‘back to normal’, whereas I used to be sleepy for several hours as my body tried to bring my electrolytes back into balance. I also would have massive unquenchable thirst during this that I now don’t have.
I have read no studies that link CSF production with electrolyte deficiencies. This is a hypothesis of my own with no backing, so take it for what it is worth. Having said that, there have been many posts on HN on the recent studies on CSF https://news.ycombinator.com/item?id=39723704. I made the connection with CSF production and electrolytes when I was reading more about CSF production and it jumped off the page at me that potassium and other electrolytes are used to create CSF. It all just came together for me why taking potassium has helped me so much.
Thank you so much for sharing your experience and your research in the other comment. I understand that it's just a hypothesis, but I had almost given up and believed that this is just how life is now. I went to the ER for heart palpitations and told the doctors to check electrolyte levels and they flat out refused and discharged me. Between this and the potential renal issues, I at least have another avenue to try to address the underlying problem.
I'll try the potassium supplements and report back. Around how much are you supplementing each day? People shy away from potassium supplementation because it can cause heart palpitations, but I already have those, similar to yours, and RDA of potassium is over 3000mg, so it's only up from here :) Thanks again.
I hear you, I was in the same boat. I had been to the doctor many times without much luck. I am outwardly healthy looking. Thin, fit with no other problems. I had a good doctor, but doctors are used to dealing with acute problems in people that are simply unhealthy. When they see me they are often dismissive that I have any real problems. I had a pretty good rapport with my doctor so he would do tests and we would have some good dialog, but he retired and, honestly, it is just too frickin difficult to go through the process of bringing a doctor up to speed on what my history is.
Fortunately for me I was able to retire at 50 and I am an avid consumer of information, so I spent an inordinate amount of time educating myself. I went down many wrong paths (as another commenter pointed out, diabetes can cause a lot of these symptoms). I wish I could say I brute forced my solution, but it was some innocuous comment on HN about potassium deficiency that made me look into it, and the rest is history. It was my “break through”, so to speak.
I take anywhere from 600mg to 800mg most days spread throughout the day depending on meals and activity level, but as much as 1000mg some days. Never all at once.
On a related note, here is the thing about measuring electrolytes – your body goes through great efforts to make sure your electrolyte levels in your blood are in balance. But here is the kicker, only sodium ‘primarily’ resides in your blood. The other electrolytes primarily reside in your other tissues. For example, potassium is mostly held inside your cells like muscle tissue. As a matter of fact, this is how muscles contract. When muscles contract, potassium temporarily moves out of the cell and sodium moves in. Then in a minute potassium and sodium reverse back to normal. This is one reason your muscles fatigue and then become usable again a short time later. When your cells are short potassium then your muscles fatigue quickly and don’t bounce back.
You can’t measure this level of potassium. Your blood levels might be just fine, but your cells may be deficient and you will never know. It is the same with calcium and magnesium (bone). If you ever get a blood test and your electrolytes are off, you probably need to be in the hospital. It means shit is so bad that your body has lost its ability to compensate. But it also means that if you go to the doctor and get your electrolytes tested, they will likely be in the normal range, but that does not mean you aren’t deficient.
Sorry for the late reply, I pick up 99mg potassium + 200mg magnesium and had an unbelievable night's sleep and many symptoms improved dramatically. The second night was confounded by an evening workout, which can mess with electrolyte levels, but you have given me hope again. I just want to thank you again for continuing the tradition of changing someone's life with an innocuous HN comment :)
I see what you mean regarding the electrolyte measurements. After reading a bit about the disorders that you mentioned, it seems like they test for serum and excreted electrolyte levels to make a diagnosis. But based on your point above, these tests can be inconclusive. Were there certain diagnostic tests that were helpful to you in coming to your conclusion, or was it largely trial and error based on symptom management?
No, I never had any tests beyond the simple blood tests checking my electrolyte levels. This was before I realized that those tests won’t show you the problem. I simply made a hypothesis and tested, over and over.
I have toyed with the idea of visiting a nephrologist, but I just can’t psych myself up for the long slog that would be. I live in a fairly large city but given the rarity of these syndromes, it would not surprise me at all if any local nephrologists have even encountered anyone with one of these conditions. I have also considered seeing a ‘functional doctor’, but just have not gone down that road. Honestly, I seem to have my symptoms under control, so what they could add at this point? There is no treatment or cure for this, only managing symptoms (assuming this is what I have, to be fair).
It all makes sense to me though. Though this is something that got bad enough for me to make a concerted effort to figure out just in the last decade, if I reflect back on my life I have seen problems associated with it back into my 20’s. In my case, I don’t think it is something that “happened” to me, but something I was born with that is just progressing as I get older.
By the way, I was re-reading a comment of yours from up above and I realized that you were referring to heart palpitations like you were already getting too much potassium. Here is the thing – you can get heart palpations from too much AND too little potassium. Also from too little calcium. Just food for thought.
I have updated my profile with my contact info. If you ever go down the route of getting diagnosed or have any other questions, feel free to contact me anytime. Good luck!
Sorry, you asked about ‘possible upstream causes of electrolyte deficiency’.
In my case I believe it is caused by an undiagnosed kidney problem loosely called ‘salt-wasting syndrome’. There are many types, but they all revolve around a genetic disorder where the tubules in your kidneys that are responsible for removing different electrolytes from the urine and retaining them are malformed and are not able to keep the electrolytes like a normal kidney does. Here are a few I found in my research:
I my particular case, I believe I have a type that does not impact sodium, but does potassium. When I eat a high sodium meal it causes me to pee a lot to try to get the my sodium levels back to normal. However, my body can’t retain potassium when it does this (and since I was eating much more sodium and much less potassium than my body required) I end up with normal sodium levels but low potassium levels. Taking potassium a few hours after a meal “fixed” this.
Short of genetic issue like this I am not sure what could cause it. I think this can be an early symptom of Diabetes, but don’t know much about that. What I am talking about here has got to be rare, so it may not be applicable to you.
Just another anecdote – when reading some of these links it made me remember another interesting symptom I used to have that I did not know was related: I would get “facial numbness”. Specifically, my lips and the immediate surrounding area would feel slightly numb. Usually in the morning after a poor night of sleep. I would remember feeling this on the way to work in the car. It would contribute to that dazed feeling I felt like I would swimming through a mental fog.
Oh, and one more! I also don’t get nearly so hung over from drinking! This was a surprise for me. I have always drank a lot of water while drinking alcohol, but I would always have the worst drained feeling the next day with such a headache. The headache would last all day. However, if I now take some potassium while drinking and throughout the night (depending on how much I drink), I often don’t have much of a hangover. This amazes me! I am 57 and used to drink a lot when I was in my 20’s. I had some friends that could be normal the next day and it always blew my mind. Now I think I know why. They have normal kidneys!
Thanks for these references; I've been going down the research rabbit hole :)
I check my A1C every six months and I'm ok. I'm in decent shape also: regularly powerlifting, running, etc. I have a suspicion that there is a genetic component for me; there are some autoimmune issues in my family that haven't been attributed to a particular disorder and there is a chance of an underlying condition causing these autoimmune-like symptoms.
I don't think I've noticed facial numbness, but my limbs fall asleep quickly and my hands fall asleep if I am reading my phone/book while lying on my back after a couple minutes. I also drink a TON of water when drinking alcohol and am hungover for days afterwards. Since my electrolyte revelation, I started knocking back pedialyte before sleeping which helped a ton.
Damn, thanks for your insights. I recently discovered how much better I sleep when fasting. During my fasts I'm taking precise amounts of electrolytes (sodium, magnesium, potassium: https://en.wikipedia.org/wiki/Oral_rehydration_therapy). Being off my fasts I'm getting sloppy with my electrolytes intake and here we are: I'm getting the same symptoms you describe. Not severely, but noticeably.
Now I need to find a proper supplement in Germany. Most electrolytes that also have the recommended amounts of glucose contain artificial sweetener which is a big no-go for daily usage for me.
Thanks for sharing- I find that these type of anecdotes often do work for other people, and are not information people can get from a doctor. I’m going to try what you suggest myself- I also tend to wake up at night and not fall back asleep, with no obvious explanation.
I find magnesium a tricky one to get right for me. I have tried most of the kinds available and have settled on magnesium chloride in a liquid form. It has a god awful taste, but has absolutely no other side effects.
Citrate causes me to have too soft of stools. Glycinate is often recommended for sleep, but for me it has the opposite effect – it wires me. I have tried taurine, malinate, and threonate, but chloride just works the best for me.
Electrolytes do ‘wear off’ in the sense that they are constantly depleted by your body, even when everything is working well. I have come up with the metaphor that electrolytes are like gas and oil in your car. They are constantly used up and need to be replenished. This is normal.
The good news is that I noticed the difference immediately!
Not OP but I've had luck with zinc and magnesium aspartate supplements commonly available on Amazon. I take two caps that each are a net about 500mg an hour before bed, along with 1mg of melatonin.
You need to be a bit careful with zinc. A doctor friend of mine compiled a load of data showing most zinc supplements are contaminated with cadmium, which is cumulative. I'm not sure if he's published yet.
Fyi in the consumerlabs review for zinc, all products passed testing for cadmium levels with the highest (Nature's Bounty) having 0.5mcg/g.
You basically need to be careful with any supplement since it's unregulated, and need to do a lot of careful diligence. It's a good sign if they are honest about their supplier and you trace back their supply chain. E.g. for many chelated supplements (zinc included), if you see a TRAACS trademark then the source is Balchem (Albion) which to my understanding is fairly well regarded.
ConsumerLabs tested one such TRAACS product and found it to be 0.1 mcg/g cadmium, so likely most products using TRAACS zinc bisglycinate formulation should be similar. I also found some EU food safety application [1] which confirms that across 3 different manufacturers of zinc bisglycinate (one of which is Albion), all samples were < 0.1mcg/g
Thanks! It is also critical to balance zinc with copper, and supplementing a lot of zinc without copper can effectively cause copper deficiency, which is very serious.
That doesn’t tell you a lot. You would have to take a bath with and without magnesium, and without knowing whether it’s with or without magnesium, and then write down the effect for each bath.
Currently, it could just be the effect of the bath itself or placebo.
If you took a bath in hot water, that has its own effects on the body, as it will lower your blood pressure, it can also relax your muscles, so you need to try it out without the magnesium to see if it did anything.
Depends what you mean by 'general supplement' but a majority of people are deficient in magnesium (~400 mg/d is the recommendation) and its ubiquitous involvement in hundreds of enzyme systems might reasonably indicate that a positive role in normal sleep patterns could be expected as reported in a number of publications. If there is no benefit then other factors are likely to be to the fore.
I experience muscle cramps. (Not restless leg syndrome. It's complicated.)
For others, be aware that magnesium supplements come in many forms. I don't tolerate magnesium citrate, the most common over the counter option. Tummy issues. After trying a handful of options, I chose magnesium glycine; no adverse effects and reasonable price.
This is not medical advice. YMMV. Consult your doctors.
> The sleep disturbances were assessed using the Athens Insomnia Scale [ 19], a self-administered psychometric questionnaire designed to evaluate sleep disorders, particularly insomnia [ 20 ]. It consists of eight items rated on a Likert scale ranging from 0 “no problem at all” to 3 “very severe” [ 20]. The total score ranges from 0 (absence of any sleep-related problems) to 24 (the most severe degree of insomnia). Severity is classified as normal for scores of 3 or less, subclinical insomnia for scores of greater than 3 but less than 6, and clinical insomnia for scores of 6 or more [19,21,22].
The contradiction is more clear when comparing the abstract:
> [...] Results: Multiple regression analyses revealed that individuals with higher AIS scores had higher daily potassium intake; potassium at dinner was especially crucial. [...]
and section 3.2:
> 3.2. Association Between AIS Score and Dietary Patterns of Sodium and Potassium
> Multiple regression analysis was conducted to investigate the association between AIS scores and dietary patterns of sodium and potassium intake (Table 3). Total daily potassium intake was inversely associated with log AIS score (β = −0.036; p = 0.034). When intake at each meal (breakfast, lunch, dinner, and snacks) was analyzed separately, only potassium intake at dinner remained significantly associated with AIS score (β = −0.066; p = 0.003), suggesting that higher potassium intake at dinner may be linked to fewer sleep disturbances. No significant associations were observed for the sodium-to-potassium ratio.
PSA: before you start supplementing potassium (or gorging on bananans or potatoes), please be aware that too moch potassium can lead to heart rhythm disturbances, and that some common medications (like anti-hypertensives) can have further predispose you to developing hyperkalemia.
While true, this is overblown. RDA for potassium intake is 3500-5000mg daily for an adult male. Most people do not get close to this amount. Potassium supplements are 99mg per pill. You have to take a lot of pills to reach that level. Getting too much potassium by eating potassium-rich foods would be difficult without an underlying kidney disorder.
Having said that, don’t be a dumb-a* and take too much of a good thing.
It depends on how you take it. If you chug almost liter of coconut water (like I did) you can get palpitations (like I did). That has >500mg potassium in a form more bioavailable than say a banana or butternut squash.
Also the RDA is not something you should have all at once. That’s a sure way to disrupt your heart.
I knew a guy that would eat a banana per beer. He would portion the bananas out beforehand, so we could tell he was serious when he showed up to a stag-do with two bunches!
Anecdotally, I always had much better sleep and mornings every time I remembered to eat a banana (or two!) before going to bed after a night of heavy drinking...
Two bananas to a potato (I assume we’re talking something like a russet, not a little red potato?) sounds generous to the potato, if we’re talking volume equivalence.
you can most definitely change the levels of components in a fried food.
the oil gets 'dirty' from extended use in frying. Why is it dirty? It's not dirt, and it's not oil breakdown (in most cases).
The oil is drawing components from the food into itself.
Forget the frying for a second; most fries are parboiled or blanched -- this also leeches material away from the vegetable, this time it leaves with the water used for blanching.
A french fry is delicious, but it's different than a potato -- even if it's made from one.
I don't know about the case of potassium specifically, but in general I thought that the bioavailability of elements can vary with different types of cooking?
There would still be potassium in there, unless it’s pulled out by the frying oil.
Elements can’t get lost in a chemical reaction. You can only change the molecule they’re part of, so it might not be processable by the human body, but the potassium isn’t going to disappear.
> Why would something being an element mean that heating it as part of a food wouldn’t act as a catalyst for some chemical interaction?
It sounds like the person thinks that chemical reactions can make elements change/disappear, which is not the case. And I specifically mentioned the Oil removing the potassium as an option.
A temperature so hot that the atoms of the potato would violently collide into each other, probably at least tens of millions of degrees and you would need something to confine the potato plasma!
I believe this too! My brother is not a fan bananas and barely registers mosquito bites. Me on the other hand am pursued mercilessly. Could also be we have different blood types but the immediate evidence we've seen is bananas :)
I sometimes buy evaporated because it is a big time-saver, but never sweetened condensed because it's quick and easy to add sugar myself, and leaves me in control of how much relative to the other ingredients.
Both are thicker, creamier, and even sweeter than milk - because even without the added sugar the natural sweetness of the milk is concentrated by the reduction, removing all that water.
The real shocking information I gained from this paper is that the AIS goes from 0-24 (0 = perfect sleep, 24 = total insomnia) and the study participants had an amazing average AIS score of 4.3 (SD 3.3)! Wow, how well all those people must sleep!
As someone scoring 12, it's pretty bad and I am suffering a lot while trying to sleep and during day time because I did not sleep well.
If my understanding of statistics, standard deviations and the standardized partial regression coefficient are correct, potassium supplementation in the evening only DECREASES this score by about 0.2178 (Beta −0.066, multiplied with SD of 3.3), which is kinda worthless.
It decreases the score. It doesn't increase the score. An increase would be harmful. The beta is negative. The abstract is wrong.
It is not worthless. For good sleep, potassium levels have to be adequate. Once one improves the level, one can move on to other factors.
As for what works for me, avoiding caffeine after 12 pm helps, as does sunlight exposure in the daytime.
With regard to a supplement stack, these help: collagen hydrolysate 12g, magnesium citrate, calcium, B6 as P5P, melatonin 4 mg, L-theanine 100-200 mg, and various sleep promoting herbs.
Ensure your BP is optimal, well below 120/80 for most people under 70.
Uncorrected acid reflux too worsens sleep, but avoiding consumption in the last three hours and also famotidine help.
The P5P form harms less if in excess. This is in contrast to the default form which is pyridoxine. I have found 20 mg of P5P twice daily to be quite useful for keeping stress spikes in check.
Regarding melatonin, newer data up to 2024 in https://pubmed.ncbi.nlm.nih.gov/38888087/ confirms that 4 mg is an optimal dose for sleep. For a discussion, search for this article on r/FoodNerds.
IIUC, Na is used like signaling medium in body and alkaline metals that isn't Na tends to reduce blood pressure, slow heartbeat and neural activity. With that in mind, it sounds reasonable that those tendency could lead to slightly deeper sleep. Or is there something else to it?
Preventing light from reaching your eyes in the morning either via sleeping mask or good blinds + making sure there are no electric lights visible. In other words: sleeping in total darkness until you want to wake up.
The original website is a news report of an article. The one he posted is from a peer-reviewed journal which has a much higher standard of reporting. The information there is reported by scientists with expertise in the field. You cannot expect the same level of rigour from journalists that try to sensationalise findings to get more clicks.
News articles have a valid purpose of popularizing journal articles for the vast majority of people who will feel lost looking at a journal article directly.
A news article should be compared to another news article, not to a journal article. A journal article can however be compared with another journal article.
I understand that the journal article you linked might be superior.
A self reported insomnia study has very poor accuracy. There is no reason in this day and age they are not using a sleep tracker to measure sleep onset.
Also, there is a correlation between potassium and magnesium levels, and they measured potassium intake, but no mention of magnesium. It is possible that the subjects with highest potassium intake also had higher magnesium levels.
I'm not saying the study is wrong, but it does make a good point to the people taking magnesium to help sleep, they should also be taking potassium. I'll be trying that over the next little bit.
Are there any studies on these studies? There are so many of them--and they're issued multiple times of day on television "news"--that there has to be one.
I systematically flag “diet” studies here. (And most medicine related, specially if not the study itself, but a random article with yellow title)
Some dietary studies are little better, some worse, but even the best, are very weak.
It’s known (from other studies, yes the irony) that people have no idea what they eat. Forget, don’t pay attention… so is difficult to draw conclusions. Also diet habits correlate to so many other habits, that is difficult to know what helps and what doesn’t.
Often is posted just a journalist view of it, not even the study (like this case) that is another red flag. Means that the article title is probably not so interesting.
Last but not least, being a forum of mainly CS nerds, you have to really weed through the comments. When speaking about law many start with “not a lawyer but” but seldom I see “not a doctor, but”. I’ve just seen too often people very opinionated about medicine topics of which they have no idea. Luckily is relatively easy to detect, but can be very misleading. The less the people know about something, the more sure they are they know it all. I need to state the obvious: never ever take medical advice at face value from HN.
I have a bottle of potassium based salt substitute that I use to supplement K. Can anyone here clarify the pros/cons of this? It's quite wretched by itself, but if used very sparingly is not bad with many foods.
As I'm sure all know, K in supplemental form is FDA regulated and one would need to take up to 1/2 a bottle to reach the RDA, whereas in salt sub form a single, unpleasant serving can get close to the RDA. I think it's in chloride form...
You will remove the last listed “choice” from the list and “take” it (presumably one “takes” a podcast by watching it). After taking each choice, you will wait for 25 minutes, during which time you are expected to fall asleep. If you do not fall asleep in those 25 minutes you will repeat this process with the now-current last item in the list.
If the list is exhausted and you are still awake, you and the program terminate.
I take potassium capsules frequently and magnesium capsules whenever I smoke, which is occasionally. Both of them were effective and help me with reducing anxiety and relieving stress.
But I already have k-intake.io registered, have hired a CTO for a potassium monitor wearable, app and data pipeline and am working on my pitch deck!
All that aside, almost all of the results they show are deep within statistical error bounds. My weight easily varies 5lbs (2kg) within a week, saying you lost that amount after a month of diet doesn't really say much to me. I could weigh myself a week from now and say I lost that, then one week on and say I regained it.
I am assuming the best thing I can do for it is lose weight, but that's easier said than done.
I don't think that's correct. Lower stomach acid pH makes the LES close more tightly, with a max around pH==3.
Having the right amount of stomach acid and low PH is crucial to keep the whole digestive system, gut motility and more running properly.
It sounds like there's this thing "PRAL" or "potential renal acid load" https://en.wikipedia.org/wiki/Potential_renal_acid_load where the affect on stomach acid can be different from a food's pH. But again, the wikipedia article links to some random people's blogs and a single research article from 2019. I'm not sure if this is well supported by research.
| The aim of this study was to investigate if a dietary supplementation containing: melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine would help patients with GERD,
| All patients of the group A (100%) reported a complete regression of symptoms after 40 days of treatment. On the other hand, 115 subjects (65.7%) of the omeprazole reported regression of symptoms in the same period
1) Don't drink while eating or exercising, drink 30min before or 2 hours later.
2) Don't lay on your belly while sitting, use your back to support your upper body.
3) Drink just as much water as your body asks, but not more.
4) Right before going to bed, don't drink and try using the bathroom.
In other words, good posture.
I also believe I have an underlying kidney disorder that was causing all sorts of subtle problems and after researching for years decided to try potassium supplements and it relieved the acute symptoms I was having (daytime sleepiness after meals) and also a whole slew of symptoms I didn’t realize I was having (poor workout performance and recovery, constant thirst from sodium/potassium imbalance, heart palpitations, especially at night when lying in bed, temperature regulation when trying to sleep, restless legs at night, and sleep quality).
Sleep was the most surprising. I used to wake at around 3am and just couldn’t get back to sleep. I still wake up to pee, but I get right back to sleep.
The single most surprising thing is the quality of my sleep. I now sleep like a rock. So unbelievably hard. And when I wake I feel so rested and more clear headed. I don’t need to sleep as many hours anymore and feel better than when i would sleep 9 hours.
Recently several sleep studies started talking about how sleep is not a passive activity, but a ‘washing’ of CSF over your brain. I could get some details wrong since I am going off of memory, but I believe the amount of CSF movement and production basically triples when you sleep. I hypothesize that this is simply your bodies way of cleaning the waste products out of your brain. Do you know what precursors are to create CSF? Electrolytes like sodium, potassium, chloride, and bicarbonate. It is my hypothesis that I was ‘using up’ all the potassium available with the first couple of sleep cycles and once it was gone I was unable to effectively create more CSF, rendering my sleep ineffective.
All I need to take is a couple of 99mg tablets right before bed (along with some magnesium chloride) and I sleep like I did when I was 10. I am 57. To say it has transformed my life would be an understatement.
Do you have any additional information about this relationship between CSF and electrolyte deficiency? Do you know anything about possible upstream causes of electrolyte deficiency? Any pointers would be super helpful.
I have read no studies that link CSF production with electrolyte deficiencies. This is a hypothesis of my own with no backing, so take it for what it is worth. Having said that, there have been many posts on HN on the recent studies on CSF https://news.ycombinator.com/item?id=39723704. I made the connection with CSF production and electrolytes when I was reading more about CSF production and it jumped off the page at me that potassium and other electrolytes are used to create CSF. It all just came together for me why taking potassium has helped me so much.
Have you been checked for diabetes? The thirst is one of the bigger symptoms.
I'll try the potassium supplements and report back. Around how much are you supplementing each day? People shy away from potassium supplementation because it can cause heart palpitations, but I already have those, similar to yours, and RDA of potassium is over 3000mg, so it's only up from here :) Thanks again.
Fortunately for me I was able to retire at 50 and I am an avid consumer of information, so I spent an inordinate amount of time educating myself. I went down many wrong paths (as another commenter pointed out, diabetes can cause a lot of these symptoms). I wish I could say I brute forced my solution, but it was some innocuous comment on HN about potassium deficiency that made me look into it, and the rest is history. It was my “break through”, so to speak.
I take anywhere from 600mg to 800mg most days spread throughout the day depending on meals and activity level, but as much as 1000mg some days. Never all at once.
On a related note, here is the thing about measuring electrolytes – your body goes through great efforts to make sure your electrolyte levels in your blood are in balance. But here is the kicker, only sodium ‘primarily’ resides in your blood. The other electrolytes primarily reside in your other tissues. For example, potassium is mostly held inside your cells like muscle tissue. As a matter of fact, this is how muscles contract. When muscles contract, potassium temporarily moves out of the cell and sodium moves in. Then in a minute potassium and sodium reverse back to normal. This is one reason your muscles fatigue and then become usable again a short time later. When your cells are short potassium then your muscles fatigue quickly and don’t bounce back.
You can’t measure this level of potassium. Your blood levels might be just fine, but your cells may be deficient and you will never know. It is the same with calcium and magnesium (bone). If you ever get a blood test and your electrolytes are off, you probably need to be in the hospital. It means shit is so bad that your body has lost its ability to compensate. But it also means that if you go to the doctor and get your electrolytes tested, they will likely be in the normal range, but that does not mean you aren’t deficient.
I see what you mean regarding the electrolyte measurements. After reading a bit about the disorders that you mentioned, it seems like they test for serum and excreted electrolyte levels to make a diagnosis. But based on your point above, these tests can be inconclusive. Were there certain diagnostic tests that were helpful to you in coming to your conclusion, or was it largely trial and error based on symptom management?
I have toyed with the idea of visiting a nephrologist, but I just can’t psych myself up for the long slog that would be. I live in a fairly large city but given the rarity of these syndromes, it would not surprise me at all if any local nephrologists have even encountered anyone with one of these conditions. I have also considered seeing a ‘functional doctor’, but just have not gone down that road. Honestly, I seem to have my symptoms under control, so what they could add at this point? There is no treatment or cure for this, only managing symptoms (assuming this is what I have, to be fair).
It all makes sense to me though. Though this is something that got bad enough for me to make a concerted effort to figure out just in the last decade, if I reflect back on my life I have seen problems associated with it back into my 20’s. In my case, I don’t think it is something that “happened” to me, but something I was born with that is just progressing as I get older.
By the way, I was re-reading a comment of yours from up above and I realized that you were referring to heart palpitations like you were already getting too much potassium. Here is the thing – you can get heart palpations from too much AND too little potassium. Also from too little calcium. Just food for thought.
I have updated my profile with my contact info. If you ever go down the route of getting diagnosed or have any other questions, feel free to contact me anytime. Good luck!
In my case I believe it is caused by an undiagnosed kidney problem loosely called ‘salt-wasting syndrome’. There are many types, but they all revolve around a genetic disorder where the tubules in your kidneys that are responsible for removing different electrolytes from the urine and retaining them are malformed and are not able to keep the electrolytes like a normal kidney does. Here are a few I found in my research:
-Bartters Syndrome- https://rarediseases.org/rare-diseases/bartters-syndrome/
Many different variants, so this is a possibility. Type 5?
-------------------------
-Gitelman syndrome- https://rarediseases.info.nih.gov/diseases/8547/gitelman-syn... Symptoms include tingling of face
————————
Fanconi Syndrome https://www.merckmanuals.com/home/kidney-and-urinary-tract-d...
I my particular case, I believe I have a type that does not impact sodium, but does potassium. When I eat a high sodium meal it causes me to pee a lot to try to get the my sodium levels back to normal. However, my body can’t retain potassium when it does this (and since I was eating much more sodium and much less potassium than my body required) I end up with normal sodium levels but low potassium levels. Taking potassium a few hours after a meal “fixed” this.
Short of genetic issue like this I am not sure what could cause it. I think this can be an early symptom of Diabetes, but don’t know much about that. What I am talking about here has got to be rare, so it may not be applicable to you.
Just another anecdote – when reading some of these links it made me remember another interesting symptom I used to have that I did not know was related: I would get “facial numbness”. Specifically, my lips and the immediate surrounding area would feel slightly numb. Usually in the morning after a poor night of sleep. I would remember feeling this on the way to work in the car. It would contribute to that dazed feeling I felt like I would swimming through a mental fog.
Oh, and one more! I also don’t get nearly so hung over from drinking! This was a surprise for me. I have always drank a lot of water while drinking alcohol, but I would always have the worst drained feeling the next day with such a headache. The headache would last all day. However, if I now take some potassium while drinking and throughout the night (depending on how much I drink), I often don’t have much of a hangover. This amazes me! I am 57 and used to drink a lot when I was in my 20’s. I had some friends that could be normal the next day and it always blew my mind. Now I think I know why. They have normal kidneys!
I check my A1C every six months and I'm ok. I'm in decent shape also: regularly powerlifting, running, etc. I have a suspicion that there is a genetic component for me; there are some autoimmune issues in my family that haven't been attributed to a particular disorder and there is a chance of an underlying condition causing these autoimmune-like symptoms.
I don't think I've noticed facial numbness, but my limbs fall asleep quickly and my hands fall asleep if I am reading my phone/book while lying on my back after a couple minutes. I also drink a TON of water when drinking alcohol and am hungover for days afterwards. Since my electrolyte revelation, I started knocking back pedialyte before sleeping which helped a ton.
Now I need to find a proper supplement in Germany. Most electrolytes that also have the recommended amounts of glucose contain artificial sweetener which is a big no-go for daily usage for me.
Citrate causes me to have too soft of stools. Glycinate is often recommended for sleep, but for me it has the opposite effect – it wires me. I have tried taurine, malinate, and threonate, but chloride just works the best for me.
Electrolytes do ‘wear off’ in the sense that they are constantly depleted by your body, even when everything is working well. I have come up with the metaphor that electrolytes are like gas and oil in your car. They are constantly used up and need to be replenished. This is normal.
The good news is that I noticed the difference immediately!
https://www.sleepfoundation.org/magnesium
https://www.healthline.com/nutrition/magnesium-types#9-Magne...
Been doing this for a lot of years now.
Edit, here's a paper by some other researchers: https://www.tandfonline.com/doi/abs/10.1080/0963748012005760...
You basically need to be careful with any supplement since it's unregulated, and need to do a lot of careful diligence. It's a good sign if they are honest about their supplier and you trace back their supply chain. E.g. for many chelated supplements (zinc included), if you see a TRAACS trademark then the source is Balchem (Albion) which to my understanding is fairly well regarded.
ConsumerLabs tested one such TRAACS product and found it to be 0.1 mcg/g cadmium, so likely most products using TRAACS zinc bisglycinate formulation should be similar. I also found some EU food safety application [1] which confirms that across 3 different manufacturers of zinc bisglycinate (one of which is Albion), all samples were < 0.1mcg/g
[1] https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa....
Magnesium Glycinate is much less likely to be a problem in this way
Afterwards I got up, went to bed, and slept like an absolute rock.
Currently, it could just be the effect of the bath itself or placebo.
Myth or Reality—Transdermal Magnesium? https://pmc.ncbi.nlm.nih.gov/articles/PMC5579607/
The short story -- As of 2017 the jury is still out as to whether something like an Epsom salt bath may be beneficial because of the magnesium.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4397399
- https://en.wikipedia.org/wiki/Glycine
- https://en.wikipedia.org/wiki/Magnesium_glycinate
---
Mg also acts on GABAergic/genic systems directly, but its benefits as a general supplement on sleep are disputed.
https://pubmed.ncbi.nlm.nih.gov/35184264/
"Observational studies suggested an association between Mg statuses and sleep quality, while the RCTs reported contradictory findings."
I experience muscle cramps. (Not restless leg syndrome. It's complicated.)
For others, be aware that magnesium supplements come in many forms. I don't tolerate magnesium citrate, the most common over the counter option. Tummy issues. After trying a handful of options, I chose magnesium glycine; no adverse effects and reasonable price.
This is not medical advice. YMMV. Consult your doctors.
Is this a typo, or something more nefarious?
From the abstract:
From the body of the paper (supported by the results):> The sleep disturbances were assessed using the Athens Insomnia Scale [ 19], a self-administered psychometric questionnaire designed to evaluate sleep disorders, particularly insomnia [ 20 ]. It consists of eight items rated on a Likert scale ranging from 0 “no problem at all” to 3 “very severe” [ 20]. The total score ranges from 0 (absence of any sleep-related problems) to 24 (the most severe degree of insomnia). Severity is classified as normal for scores of 3 or less, subclinical insomnia for scores of greater than 3 but less than 6, and clinical insomnia for scores of 6 or more [19,21,22].
> [...] Results: Multiple regression analyses revealed that individuals with higher AIS scores had higher daily potassium intake; potassium at dinner was especially crucial. [...]
and section 3.2:
> 3.2. Association Between AIS Score and Dietary Patterns of Sodium and Potassium > Multiple regression analysis was conducted to investigate the association between AIS scores and dietary patterns of sodium and potassium intake (Table 3). Total daily potassium intake was inversely associated with log AIS score (β = −0.036; p = 0.034). When intake at each meal (breakfast, lunch, dinner, and snacks) was analyzed separately, only potassium intake at dinner remained significantly associated with AIS score (β = −0.066; p = 0.003), suggesting that higher potassium intake at dinner may be linked to fewer sleep disturbances. No significant associations were observed for the sodium-to-potassium ratio.
I mean it's a very short paper, and the main findings are repeated, so not like it's buried.
[1]: https://pmc.ncbi.nlm.nih.gov/articles/PMC7944958/
Having said that, don’t be a dumb-a* and take too much of a good thing.
Also the RDA is not something you should have all at once. That’s a sure way to disrupt your heart.
https://my.clevelandclinic.org/health/diseases/22416-heart-p...
For what it’s worth, it’s actually nothing.
https://en.m.wikipedia.org/wiki/Banana_equivalent_dose
Usually had it with a hot curry at dinner time or dessert (sliced bananas, cubed apples and evaparoted milk.)
The only myth is that bananas are a unique source of potassium. A lot of foods have similar or more amounts of potassium per serving or by weight.
A potato’s a meal. A banana’s a lightish snack.
No carbs, no sugars, no fiber induced bloating, could easily get more than 100g into a meal
My understanding is potassium also competes with salt in the body
the oil gets 'dirty' from extended use in frying. Why is it dirty? It's not dirt, and it's not oil breakdown (in most cases).
The oil is drawing components from the food into itself.
Forget the frying for a second; most fries are parboiled or blanched -- this also leeches material away from the vegetable, this time it leaves with the water used for blanching.
A french fry is delicious, but it's different than a potato -- even if it's made from one.
Elements can’t get lost in a chemical reaction. You can only change the molecule they’re part of, so it might not be processable by the human body, but the potassium isn’t going to disappear.
The fact that the element cannot physically vanish into thin air is not really relevant here
> Why would something being an element mean that heating it as part of a food wouldn’t act as a catalyst for some chemical interaction?
It sounds like the person thinks that chemical reactions can make elements change/disappear, which is not the case. And I specifically mentioned the Oil removing the potassium as an option.
And once that's done, The Sims has almost loaded.
Learned it from first hand experience.
The surprising bit is how far you can get into a meal that looks right before you realise it really is not.
I sometimes buy evaporated because it is a big time-saver, but never sweetened condensed because it's quick and easy to add sugar myself, and leaves me in control of how much relative to the other ingredients.
Both are thicker, creamier, and even sweeter than milk - because even without the added sugar the natural sweetness of the milk is concentrated by the reduction, removing all that water.
As someone scoring 12, it's pretty bad and I am suffering a lot while trying to sleep and during day time because I did not sleep well.
If my understanding of statistics, standard deviations and the standardized partial regression coefficient are correct, potassium supplementation in the evening only DECREASES this score by about 0.2178 (Beta −0.066, multiplied with SD of 3.3), which is kinda worthless.
Please correct me if I am wrong.
It is not worthless. For good sleep, potassium levels have to be adequate. Once one improves the level, one can move on to other factors.
As for what works for me, avoiding caffeine after 12 pm helps, as does sunlight exposure in the daytime.
With regard to a supplement stack, these help: collagen hydrolysate 12g, magnesium citrate, calcium, B6 as P5P, melatonin 4 mg, L-theanine 100-200 mg, and various sleep promoting herbs.
Ensure your BP is optimal, well below 120/80 for most people under 70.
Uncorrected acid reflux too worsens sleep, but avoiding consumption in the last three hours and also famotidine help.
Yes DECREASE instead of INCREASE. What I was going for in my head was "improve" I guess. Thanks for pointing that out.
> B6 as P5P
Don't forget it's one of the few nutrients that accumulates and that you can get too much of. It causes nerve damage and mystery sores.
> melatonin 4 mg
That's probably too much:
https://www.lesswrong.com/posts/E4cKD9iTWHaE7f3AJ/melatonin-...
Regarding melatonin, newer data up to 2024 in https://pubmed.ncbi.nlm.nih.gov/38888087/ confirms that 4 mg is an optimal dose for sleep. For a discussion, search for this article on r/FoodNerds.
https://toolonline.net/en/AIS, https://www.med.upenn.edu/cbti/assets/user-content/documents...
Re-Balancing One Essential Nutrient to Protect against Stroke:
https://www.youtube.com/watch?v=liW9F6gLwgQ
If anything, increase the number of hours without eating before bed.
A recent one:
- https://jcsm.aasm.org/doi/10.5664/jcsm.10168
Many, many more
A news article should be compared to another news article, not to a journal article. A journal article can however be compared with another journal article.
I understand that the journal article you linked might be superior.
Also, there is a correlation between potassium and magnesium levels, and they measured potassium intake, but no mention of magnesium. It is possible that the subjects with highest potassium intake also had higher magnesium levels.
I'm not saying the study is wrong, but it does make a good point to the people taking magnesium to help sleep, they should also be taking potassium. I'll be trying that over the next little bit.
Some dietary studies are little better, some worse, but even the best, are very weak.
It’s known (from other studies, yes the irony) that people have no idea what they eat. Forget, don’t pay attention… so is difficult to draw conclusions. Also diet habits correlate to so many other habits, that is difficult to know what helps and what doesn’t.
Often is posted just a journalist view of it, not even the study (like this case) that is another red flag. Means that the article title is probably not so interesting.
Last but not least, being a forum of mainly CS nerds, you have to really weed through the comments. When speaking about law many start with “not a lawyer but” but seldom I see “not a doctor, but”. I’ve just seen too often people very opinionated about medicine topics of which they have no idea. Luckily is relatively easy to detect, but can be very misleading. The less the people know about something, the more sure they are they know it all. I need to state the obvious: never ever take medical advice at face value from HN.
As I'm sure all know, K in supplemental form is FDA regulated and one would need to take up to 1/2 a bottle to reach the RDA, whereas in salt sub form a single, unpleasant serving can get close to the RDA. I think it's in chloride form...
Edit: fsckin android keypad
while choices and not sleep:
[1] https://imgur.com/a/aolYez5
(After the um actually quiz show)